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GB11163 Anti -PPAR alpha Rabbit pAb

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GB11163 Anti -PPAR alpha Rabbit pAb

Peroxisome proliferator-activated receptor alpha (PPAR-alpha), also known as NR1C1, is a nuclear receptor protein that in humans is encoded by the PPARA gene.

PPAR-alpha is a transcription factor and a major regulator of lipid metabolism in the liver. PPAR-alpha is activated under conditions of energy deprivation and is necessary for the process of ketogenesis, a key adaptive response to prolonged fasting.[7] Activation of PPAR-alpha promotes uptake, utilization, and catabolism of fatty acids by upregulation of genes involved in fatty acid transport, fatty acid binding and activation, and peroxisomal and mitochondrial fatty acid β-oxidation.

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Immunohistochemistry analysis of paraffin-embedded mouse colon using PPAR alpha (GB11163) at dilution of 1: 300.
Immunohistochemistry analysis of paraffin-embedded mouse kidney using PPAR alpha (GB11163) at dilution of 1: 400.

Immunohistochemistry analysis of paraffin-embedded rat liver using

PPAR alpha (GB11163) at dilution of 1: 300.

 

Technical Specification

Storage

Storage Store at -20ºC for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100µg/ml BSA and 50% glycerol.

 

NOTE:

  1. This product is intended for research only.
  2. This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

 

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